Pulsed ultrasound on injury response process involves which cell type?

Pulsed ultrasound on injury response process involves which cell type?

• A. Mast cells
• B. Neutrophils
• C. Lymphocytes
• D. Epithelial cells

Answer: (A)

Pulsed ultrasound can stimulate the early inflammatory response by activating resident mast cells in connective tissue. These cells are positioned to sense mechanical cues, and when triggered they degranulate, releasing histamine, prostaglandins, and other mediators. This release promotes vasodilation and increased vascular permeability, creating the local environment needed to recruit neutrophils and begin the healing process. The pulsed, non-thermal nature of the therapy provides just enough mechanical stimulation to elicit this response without excessive heating. Neutrophils and later immune cells participate as the response progresses, but the initial mechanical-triggered event in this context is mast cell degranulation. Lymphocytes and epithelial cells aren’t the primary responders to this acute, mechanical stimulus in the injured tissue.

Pulsed ultrasound can stimulate the early inflammatory response by activating resident mast cells in connective tissue. These cells are positioned to sense mechanical cues, and when triggered they degranulate, releasing histamine, prostaglandins, and other mediators. This release promotes vasodilation and increased vascular permeability, creating the local environment needed to recruit neutrophils and begin the healing process. The pulsed, non-thermal nature of the therapy provides just enough mechanical stimulation to elicit this response without excessive heating. Neutrophils and later immune cells participate as the response progresses, but the initial mechanical-triggered event in this context is mast cell degranulation. Lymphocytes and epithelial cells aren’t the primary responders to this acute, mechanical stimulus in the injured tissue.